血管緊張素Ⅱ對大鼠胰島β細胞形態(tài)功能的影響

血管緊張素Ⅱ對大鼠胰島β細胞形態(tài)功能的影響

作者：劉萍，何嵐，王毅，李建寧，葉楓，劉治全
【關鍵詞】 血管緊張素Ⅱ；鹽；胰島β細胞；高血壓;大鼠
　　Effects of angiotensin II on morphology and function of islets βcells in rats
　　【Abstract】 AIM: To study the effects of angiotensin II (AngⅡ) on the function and morphology of islets βcells. METHODS: The SD rats accepted AngⅡ by hypodermic injection with the osmotic minipump for 2 weeks. Hereafter, they were fed with a normal (8 g/L NaCl) or highsalt (40 g/L NaCl) diet respectively. The following indexes, including blood pressure, fasting blood glucose, insulin and the morphology of islets βcells were observed. RESULTS: The blood pressure of rats was significantly elevated 2 weeks after accepting AngⅡ via chronic hypodermic injection; at the end of 4 weeks, compared with control group, the blood pressure was increased unceasingly and markedly in the rat with AngⅡ infusions; meanwhile, the areas of islets βcells in the rats of highsalt diet became larger than those of control group (P

【血管緊張素Ⅱ對大鼠胰島β細胞形態(tài)功能的影響】相關文章：

吡格列酮對代謝綜合征患者血管內皮細胞功能的影響03-30

血管緊張素Ⅱ受體拮抗劑對高血壓病患者左室重構的影響03-06

振動刺激對廢用性肌萎縮大鼠肌纖維形態(tài)結構的影響03-03

淺論川芎嗪對內皮祖細胞的功能影響03-08

談石杉堿甲對老年大鼠腹部手術術后認知功能的影響03-19

電針和半夏瀉心湯對功能性消化不良大鼠胃動素的影響03-03

羧基肽酶-H抗體與LADA患者胰島功能關系03-08

模擬失重對成骨細胞整合素亞單位表達的影響12-04

探討體外培養(yǎng)的大鼠松果體細胞分泌的松果體素在持續(xù)黑暗的環(huán)境下03-03

超短波對大鼠坐骨神經損傷后血管內皮生長因子表達的影響03-08