經皮冠狀動脈內支架植入術對外周血單核細胞NF

經皮冠狀動脈內支架植入術對外周血單核細胞NF

作者：王暉，楊志健，黃峻，朱鐵兵，王連生，曹克將
【關鍵詞】 ,外周血單核細胞
Activation of NFκB induced by coronary stent placement in peripheral blood mononuclear cells
　　【Abstract】 AIM: To investigate the effect of coronary stenting on the activation of NFκB in peripheral blood mononuclear cells (PBMC). METHODS: Fifty patients were classified into two groups: 28 patients in stenttreatment group and 22 in coronary angiography (CAG). The levels of NFκB activity preprocedural and during the days after stent placement were determined using electrophoresis mobility shift assay (EMSA). RESULTS: The levels of NFκB activity in stenttreatment group from preprocedural to the 4th hour, 1st, 2nd and 3rd days after stent placement were (1.17±0.25) fold, (1.23±0.30) fold, (2.00±0.45) (2.49±0.46) fold and (2.25±0.4) fold respectively. Significantly increased levels of NFκB activity were seen in the 1st, 2nd and 3rd days (P

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