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2017公衛執業醫師考試《醫學微生物學》基礎題及答案
基礎題一:
1.細菌的革蘭染色性主要決定于:( )
A.核質結構 B.細胞壁結構 C.細胞膜結構
D.磷壁酸的有無 E.中介體的有無
2.溶原性細菌是指:( )
A.帶有前噬菌體基因組的細菌 B.帶有毒性噬菌體的細菌
C.帶有溫和噬菌體的細菌 D.帶有R質粒的細菌
E.帶有F質粒的細菌
3.能引起內毒素性休克的細菌成分是:( )
A.肽聚糖 B.磷壁酸 C.LPS D.菌體抗原 E.莢膜多糖
4.關于頓挫感染,下列敘述中哪項正確?( )
A. 因宿主細胞內有相應抑制物 B. 因宿主細胞DNA有關基因激活
C. 因宿主細胞缺乏有關酶 D. 因感染病毒有核酸缺失
E. 因感染病毒抗原性轉變
5.細菌芽胞特有的、并與其高度耐熱性有關的成分是:( )
A.磷脂 B.肽聚糖 C.磷壁酸
D.二氨基庚二酸 E.吡啶二羧酸
6.下列哪種實驗可用來檢測致癌物質?( )
A.Ames test B.transformation test
C.fluctuation test D.replica plating test
E.Widal test
7.殺滅包括芽胞的所有微生物的方法稱作: ( )
A.消毒 B.無菌 C.滅菌 D.滅活 E.防腐
8. 下列無芽胞的細菌中,抵抗力最強的是: ( )
A. 乙型溶血性鏈球菌 B. 金黃色葡萄球菌 C. 淋病奈瑟菌
D. 肺炎球菌 E. 腦膜炎奈瑟菌
9. 下列哪項不是病毒在細胞內增殖的指標?( )
A. 細胞病變效應 B. 紅細胞吸附 C. 細胞代謝的改變
D. 干擾現象 E. 細胞培養液混濁
10.霍亂弧菌能粘附定植于小腸粘膜上皮細胞是因為具有:( )
A.鞭毛 B.LTA C.菌毛 D.K抗原 E.Vi抗原
11.對青霉素產生耐藥性的最常見的細菌是:( )
A.Streptococcus B.Staphylococcus C.Meningococcus
D.Gonococcus E.Pneumococcus
12.分枝桿菌屬最突出的特點是:( )
A.胞壁含大量脂質 B.無特殊結構 C.呈分枝生長
D.一般不易著色 E.抗鹽酸乙醇脫色
13. 下列哪種物質與結核結節和干酪樣壞死有關?( )
A.分枝菌酸 B.蠟質D C.磷脂
D.索狀因子 E.硫酸腦苷脂
14.下列哪種細菌不會引起食物中毒:( )
A. 鼠傷寒沙門菌 B. 志賀菌 C. 蠟樣芽胞桿菌
D. 希氏沙門菌 E. 產腸毒素的金黃色葡萄球菌
15.從有正常菌群存在的部位所采取的標本應接種在哪種培養基中分離培養病原菌? ( )
A.增菌培養基 B.營養培養基 C.選擇鑒別培養基
D.基礎培養基 E.特殊培養基
16.衣原體與病毒的相同點是:( )
A.含有RNA和DNA B.有核糖體 C.嚴格細胞內寄生
D.二分裂方式繁殖 E.對抗生素敏感
17.新生隱球菌致病物質主要是:( )
A.莢膜多糖 B.芽生孢子 C.細胞壁
D.假菌絲 E.侵襲性酶
18.真菌的假菌絲是由哪種孢子延長而形成的? ( )
A.芽生孢子 B.大分生孢子 C.小分生孢子
D.關節孢子 E.厚膜孢子
19.The main infection source of epidemic type B encephalitis virus is: ( )
A. patient B. health carrier C. young pig D. culicine(庫蚊) E. louse
20.The main type of infection caused by Poliovirus is:( )
A.inappareent infection B.acute infection C.chronic infection
D.latent infection E.slow virus infection
21.At an office visit, a 38-year-old man complains of jaundice黃疸, dark urine, anorexia厭食, abdominal pain, and malaise不適. Serologic tests are positive for both HBeAg and HbsAg. Which statement most accurately describes the virus responsible for these findings? ( )
A. Its genome is a messenger RNA (mRNA) that encodes a polyprotein.
B. Its genome is linear double-stranded DNA.
C. Its genome is RNA, but it replicates through a DNA intermediate.
D. Its replication requires a helper virus.
E. Its replication requires an RNA-dependent DNA polymerase.
22. Which step in viral replication is inhibited by protease inhibitor? ( )
A. Penetration
B. Uncoating
C. Transcription
D. Replication
E. Viral assembly
23. A 48-year-old man has been receiving blood products for hemophilia血友病 since childhood. He is now suffering from a low-grade fever, weight loss, thrush鵝口瘡, serious bouts of diarrhea, and symptoms of pneumonia. A deficiency in the production of which substance would be most pronounced in this patient? ( )
A. Complement components
B. Immunoglobulin G (IgG)
C. Interferon-alpha (IFN-α)
D. Interferon-gamma (IFN-γ)
E. Interleukin-1 (IL-1)
24.A neonate is born with a small head, intracerebral calcification腦內鈣化, rash, and swollen liver and spleen. Cells with a basophilic nuclear inclusion body are obtained from the patient’s urine, which condition describes the most prevalent consequenence of adult infection with this agent? ( )
A. Immunosuppression and susceptibility to opportunistic diseases
B. Mild arthritic condition with a fine lacy rash
C. Mononucleosis with production of antibody to sheep red blood cells
D. No serious, definable disease symptoms
E. Pharyngoconjunctivitis咽結膜炎
25.A virus isolated from a patient with liver disease is detergent去污劑-sensitive, and its genome is infectious, Which virus do these findings describe? ( )
A. Echovirus
B. Hepatitis A virus
C. Hepatitis C virus
D. Hepatitis E virus
E. Papillomavirus
參考答案
1. B 2 . A 3. C 4. C 5. E 6. A 7. C 8. B 9. E 10. C
11. B 12. E 13. C 14. B 15. C 16. C 17. A 18. A 19. C 20. A
21. E 22. E 23. D 24. D 25. C
基礎題二:
C1.大多數細菌生長繁殖的最適pH值范圍適
A.4.0~6.0 B.5.5~6.5 C.7.2~7.6 D.8.0~9.0 E.8.4~9.2
B2.細菌藥物敏感性的測定及保存菌種多選用細菌生長繁殖的哪個期
A.適應期 B.對數生長期 C.穩定期 D.遲緩期 E.衰亡期
B3.吲哚試驗陽性的細菌,是因為它能分解
A.胱氨酸 B.色氨酸 C.葡萄糖 D.枸櫞酸鹽 E.乳糖
B4.細菌生長繁殖的方式是以
A.孢子出芽方式 B.二分裂法方式
C.增殖方式 D.自我復制方式
E.有絲分裂方式
B5."菌落"是指
A.細菌在固體培養基上生長繁殖而形成肉眼可見的細胞集團
B.一個細菌在固體培養基上生長繁殖而形成肉眼可見的細胞集團
C.一個菌細胞
D.不同種的細菌在液體培養基上形成肉眼可見的細胞集團
E.細菌在營養培養基上生長繁殖而形成肉眼可見的細胞集團
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